Student written Research Laboratory Guidebook 2023Nagaoka University of Technology

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21

Laboratory for Molecular Physiology

Professor / Koichi TAKIMOTO

ProfessorKoichi TAKIMOTO

profiles and activiities profiles and activiities at nagaoka university of technology
J-GLOBAL
  • Exposing the mechanism of potassium channels
  • Protease inhibitors as Kv channel gating modifiers
  • Researching the how and why of adipocyte browning

Supervisor

Professor / TAKIMOTO Koichi
Having worked in the United States for a long time, our professor emphasizes on nurturing self-management skills and advise his students to be free, but responsible for their actions. As the professor has a broad knowledge in various areas, he could give advices for both our research and daily studies.

Research Content

Our laboratory focus on investigating the mechanism of potassium ion channels, particularly those of the EAG subfamily group. These ion channels have been shown to be highly expressed in several types of cancer, and is considered as a potential target in cancer treatment. By researching these ion channels and the peptides derived from it, we hope to elucidate its effect on cell growth, and examine its viability as a treatment target.
In addition, our lab also conduct research on the browning of adipose tissues, by introducing various chemicals into the adipocyte and evaluating its browning reaction

Determining cell growth using alamar-blue reagent

A Day in the Lab

Students are allowed to do research at their own convenience, as there is no fixed schedule in our lab, although every lab members are required to attend the weekly journal club and report their research progress to the professor once a week. Students also have a lot of opportunities to discuss and ask for any advice from the professor regarding their research, studies, or life in general.
Other than general lab work, we participate in the university’s softball
tournament and irregularly goes out for nomikai.

Group photo of lab members during softball tournament

Thesis Subjects

  • (M)Effect of EAG2 channel-derived peptides on cell proliferation : Comparison with EAG1 channel and examination of cell specifity
  • (M)Changes in Kv channel opening/closing mechanism by protease inhibitors : Identifying modified amino acids by drug admission

The number of
PhD Graduates

0

Major employers of Graduates

  • Nipro Pharma
  • Denka Seiken
  • Toyo Roshi Kaisha, Ltd.
  • Asahi Diamond Industrial
  • Roche Diagnostics
  • Showa Rekisei Industries
  • Hokuriku Gas
  • Beckman Coulter
Writer : Eisuke HARADA, Bioengineering
(National Institute of Technology, Numazu College)