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Stem Cell Thechnology Laboratory
Associate Professor / OHNUMA Kiyoshi
- Producing high quality research related to regenerative medicine
- Understand the mechanism of human embryogenesis
- Establishing a work-life balance in aboratory
Associate Professor / OHNUMA Kiyoshi
Our sensei always share significant wisdom and great advice with us. He thinks about students' futures carefully. Sensei is dedicated to educating students even though he is very busy. He is a good-hearted sensei who teaches the student with a gracious speech. For this reason, students can discuss freely with him in everything, especially academic work and living.
Research Content
Pluripotent Stem cells (PSCs) can differentiate into all types of cells and divide almost infinitely. Thus, human iPSCs are pivotal for achievements in regenerative medicine and drug discovery. We are dedicated to developing innovative technologies alongside the application of stem cells for biomedical purposes. We employ human induced pluripotent stem cells (iPSCs) to address research challenges in vitro and in vivo.
Our major research topics include;
(1)Human-Zebrafish xenograft models for heart regeneration research
(2)Development of microfluidic devices to control human iPSCs differentiation and drug discover
(3)Mimicking human embryo self-organization mimicking for testing teratogenic drugs.
Our major research topics include;
(1)Human-Zebrafish xenograft models for heart regeneration research
(2)Development of microfluidic devices to control human iPSCs differentiation and drug discover
(3)Mimicking human embryo self-organization mimicking for testing teratogenic drugs.
Culture iPSC in this device
A Day in the Lab
Our laboratory begins every day with a short meeting at 9:30 am. All lab members discuss the daily agenda and share information about academic events. Lab members will engage in study freely according to their own schedules. Each research group presents and discusses twice a month to confirm the progress and for the future schedule.
Normally, we meet in the laboratory daily, increasing all members' closeness.
We sometimes hold laboratory parties to commemorate members' graduations and thesis acceptances.(following the guidance of covid -19 prevention).
Normally, we meet in the laboratory daily, increasing all members' closeness.
We sometimes hold laboratory parties to commemorate members' graduations and thesis acceptances.(following the guidance of covid -19 prevention).
Good atmosphere in laboratory
Thesis Subjects
- (D)Gravity-driven microfluidic device placed on a slow-tilting table enables constant unidirectional perfusion culture of human induced pluripotent stem cells
- (D)Xenograft of human pluripotent stem cell-derived cardiac lineage cells on zebrafish embryo heart
- (D)Thalidomide induces apoptosis during early mesoderm differentiation of human induced pluripotent stem cells
The number of
PhD Graduates
2
Major employers of Graduates
- iHeart Japan Co., Ltd.
- NAKABOHTEC CORROSION PROTECTING CO., LTD
- Kracie Pharmaceutical Co., Ltd.
- Fuso Pharmaceutical Co., Ltd.
- Nipro Pharma Corporation
- Japan Atomic Energy Agency
- Nipponham Delicatessen Ltd.C
- Japan Nuclear Fuel Limited
- Showa Denko Materials Co., Ltd.
- Micron Memory Japan, G.K.
