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Stem Cell Technology Laboratory
Associate Professor / OHNUMA Kiyoshi
- Producing fish with human hearts to study heart regeneration
- Understand the mechanism of human embryogenesis
- Human-mimicking chips as an altanative to animal testing
Associate Professor / OHNUMA Kiyoshi
Associate Professor Ohnuma always gives us valuable advice. He carefully considers students’ futures. Sensei is dedicated to educating students even though he is very busy. He is a good-hearted sensei who teaches his students with a gracious demeanor. For this reason, students can discuss freely with him about everything, especially academic work and living.
Research Content
Pluripotent Stem cells (PSCs) can differentiate into all types of cells and divide almost infinitely. Thus, human iPSCs are pivotal for achievements in regenerative medicine and drug discovery. We are dedicated to developing innovative technologies alongside the application of stem cells for biomedical purposes. We employ human induced pluripotent stem cells (iPSCs) to address research challenges in vitro and in vivo.
Our major research topics include;
(1)Human-Zebrafish xenograft models for heart regeneration research
(2)Development of microfluidic devices to control human iPSCs differentiation and drug discovery
(3)Mimicking human embryo self-organization for testing teratogenic drugs.
Our major research topics include;
(1)Human-Zebrafish xenograft models for heart regeneration research
(2)Development of microfluidic devices to control human iPSCs differentiation and drug discovery
(3)Mimicking human embryo self-organization for testing teratogenic drugs.
Culture iPSC in this device
A Day in the Lab
Our laboratory begins every day with a short meeting at 10:30 am. All lab members discuss the daily agenda and share information about academic events. Lab members study freely according to their own schedules. Each research group presents and discusses twice a month to confirm progress and discuss future schedule.
Normally, we meet in the laboratory daily, increasing interaction among members.
We sometimes hold laboratory parties to commemorate members’ graduations and thesis acceptances.
Normally, we meet in the laboratory daily, increasing interaction among members.
We sometimes hold laboratory parties to commemorate members’ graduations and thesis acceptances.
Good atmosphere in laboratory
Thesis Subjects
- (M)Mimicking the Dynamics of Human Embryonic Gastrulation Using Printed Culture of Human Induced Pluripotent Stem Cells
- (M)Development of a multi-organ cell culture microfluidic device using polystyrene as a culture substrate for toxicity testing
- (M)Cardiotoxicity Assessment of Human iPS Cell-Derived Cardiomyocytes Transplanted into Zebrafish Embryos
The number of
PhD Graduates
5
Major employers of Graduates
- Shin Nippon Biomedical Laboratories, Ltd.
- Hokuren Federation of Agricultural Cooperatives
- iHeart Japan Co., Ltd
- Asahi Intecc Co., Ltd.
- Japan Nuclear Fuel, Ltd.
- Kracie, Ltd.
- Nipro Pharma Co., Ltd.
- Fuso Pharmaceutical Industries,Ltd.
- I Medex Co., Ltd.
- Japan Atomic Energy Agency
