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Laboratory of Organic Reaction Design and Synthesis
Professor / MAEKAWA Hirofumi
Technical Staff / KAWAHARA Natsue
- Enjoy synthetic reactions like puzzle of compounds!
- Design your original reactions and make them true!
- Synthesize complicated compounds with high techniques!
Professor / MAEKAWA Hirofumi
Prof. Maekawa is very serious and strict in research, but he is quite friendly. Our conversation with him is always fascinating and a variety of topics are taken up. The knowledge of chemistry and his attitude towards research that he suggests to us are great help for us in advancing our research.
Research Content
In recent years, eco-friendly and efficient reactions have been required with no harmful substance and less amount of reagents. In our laboratory, novel synthetic organic reactions characterized by high selectivity, low cost, and easy method are designed, tried and developed by use of magnesium metal with low toxicity and high reducing potential. In these reactions, coupling reactions between electrophilic carbon atoms can be archived because one electrophilic carbon atom is converted into a nucleophilic one, which cannot be found in textbooks for beginners. Application of our reactions to preparation for organic materials may greatly shorten synthetic reaction steps.
Typical apparatus of a reductive coupling reaction by magnesium metal
A Day in the Lab
Our laboratory has no core time and students proceed on their experiments at their own pace. However, self-management ability and autonomy will be strongly cultivated because superior planning of experiments is required. Every week, we hold a seminar to discuss the latest papers and a seminar to study organic reactions and recent topics in organic synthesis. Through these seminars, students also learn how to make questions and answer the questions. In our laboratory, the office and the laboratory are adjacent to each other, so you can immediately get advice from laboratory members if you are stuck in your research.
TOF high resolution mass spectrometer. We analyze synthesized compounds by ourselves and determine their chemical structures.
Thesis Subjects
- (D)Studies on Novel Transformation of Aromatic Compounds through Reductive Activation of π-Electron System
- (M)Magnesium-promoted reductive coupling of 4-vinylpyridine and methyl methacrylate
- (B)Reductive coupling reactions of diphenylfulvene with silylating agents by magnesium
The number of
PhD Graduates
13
Major employers of Graduates
- Fujifilm Wako Chemical Corporation
- Light Chemical Industries Co., Ltd.
- Osaka Gas Chemicals Co., Ltd.
- Kawaken Fine Chemicals Co., Ltd.
- Nippeco Ltd.
- Orient Chemical Industries Co., Ltd.
- Fujifilm Wako Pure Chemical Corporation
