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Laboratory of Organic Reaction Design and Synthesis
Professor / Hirofumi MAEKAWA
Assistant Professor / Tianyuan ZHANG
Technical Staff / Natsue KAWAHARA
ProfessorHirofumi MAEKAWA
| profiles and activiities | profiles and activiities at nagaoka university of technology |
|---|---|
| J-GLOBAL |  |
Assistant ProfessorTianyuan ZHANG
| profiles and activiities | profiles and activiities at nagaoka university of technology |
|---|---|
| J-GLOBAL | |
- Enjoy synthetic reactions like puzzles of compounds !
- Design your original reactions and make them true !
- Synthesize complicated compounds with your high techniques !
Supervisor
Professor / Hirofumi MAEKAWA
Prof. Maekawa is very serious and strict in research , but he is quite friendly. Our conversation with him is always fascinating and a variety of topics are taken up. The knowledge of chemistry and his attitude towards research that he suggests to us are great help for us in advancing our research.
Research Content
In recent years, eco-friendly and efficient reactions have been required with no harmful substance and less amount of reagents. In our laboratory, novel synthetic organic reactions characterized by high selectivity, low cost, and easy method are designed, tried and developed by use of magnesium metal with low toxicity and high reducing potential. In these reactions, coupling reactions between electrophilic carbon atoms can be achieved because one electrophilic carbon atom is converted into a nucleophilic one, which cannot be found in textbooks for beginners. Application of our reactions to preparation for organicmaterials may greatly shorten synthetic reaction steps.
Typical apparatus of a reductive coupling reaction by magnesium metal
A Day in the Lab
In our laboratory, students start to have experiments every morning around 9 am. There is no core time and students proceed on their experiments at their own pace. However, self-management ability and autonomy will be strongly cultivated because superior planning of experiments is required. Every week, we hold a seminar to discuss the latest papers and a seminar to study organic reactions and recent topics in organic synthesis. One of the purposes of the latter seminar is learning how to make questions and how to answer the questions. All members are friendly and we often talk about our research topics each other.
TOF high resolution mass spectrometer can be used to decide the structure and composition of organic compounds.
Thesis Subjects
- (M)Reduction of azulenes to introduce a functional group to the seven-membered ring
- (M)Magnesium-promoted reductive coupling of benzoylsilane and methyl acrylate
- (M)Reductive coupling reactions of α-silylstyrenes with silylating agents by calcium
The number of
PhD Graduates
11
Major employers of Graduates
- IVY Cosmetics
- Osaka Gas Chemicals Co., Ltd.
- Nippeco Ltd.
- Kyoeisha Chemical Co., Ltd.
- Fujifilm Wako Pure Chemical Corporation
- Fujifilm Wako Chemical Corporation
- Toray Industries, Inc.
- Orient Chemical Industries Co.,Ltd.
- Howa Sangyo Co., Ltd.
- Kawaken Fine Chemicals Co.,Ltd.
